IUI With 2 Follicles

Intrauterine insemination (IUI) is a fertility procedure in which sperm is inserted directly into a woman’s uterus to assist fertilization. The success of IUI can often hinge on the number of follicles present during the treatment. Particularly, IUI with 2 follicles is considered by many fertility specialists to improve the chances of pregnancy, compared to just one follicle.

Dr. Hrishikesh Pai and Dr. Nandita Palshetkar, highly experienced IVF doctors in Mumbai at Babies and Us, have extensive experience in reproductive medicine, especially in IUI, IVF, and ICSI treatments. Their expertise has been instrumental in enhancing the outcomes of IUI procedures, especially in cases involving multiple follicles.

Interested in exploring fertility options? Consult with a fertility expert and get tailored guidance and care. Book your appointment today to discuss your options.

Considering increasing your family? What better way to understand your options than to dive deeper? 

What does IUI with 2 follicles mean?

IUI with 2 follicles means stimulating the ovaries to develop two mature follicles instead of just one. This is achieved through medication that encourages ovarian stimulation. “Having two follicles increases the odds of successful fertilization as it boosts the number of available eggs during IUI,” explains Dr. Hrishikesh Pai.

The rationale behind promoting the development of two follicles is based on the statistical improvement in pregnancy rates observed in various studies.

Dr. Nandita Palshetkar notes, “By optimizing the number of follicles, we can potentially enhance the effectiveness of the IUI procedure without significantly increasing the risk of high-order multiple pregnancies.”

Looking for expert advice on your fertility options? Consult with an IUI professional to clarify the best path forward for your reproductive health. Schedule a visit today.

Curious about the potential benefits or risks? Let’s explore what you can expect.

Benefits/Risks of IUI with 2 follicles

Benefits	Risks
Increased chances of conception	Higher chance of multiples
Cost-effective compared to IVF	Possibility of ovarian hyperstimulation syndrome (OHSS)
Less invasive than IVF	Potential for ectopic pregnancy
Shorter treatment time	Emotional and physical strain
Can be done with donor sperm	May need repeated cycles
Improved response to hormones	Variability in individual responses

Are you thinking about success rates? Let’s look at the possibilities with IUI involving two follicles.

Success Rates of IUI with 2 follicles

The success rates of 2 follicles for IUI are promising. Studies indicate that the chance of pregnancy increases when two mature follicles are present compared to just one. This is primarily due to the increased likelihood of at least one egg being fertilized.

However, success rates can vary widely based on individual factors such as age, underlying fertility issues, and the quality of the sperm used. It is essential to have realistic expectations and discuss these with a fertility specialist to understand how your specific circumstances may affect the outcomes.

Considering fertility treatment? Seek advice tailored to your unique situation from a fertility expert to explore your options.

Wondering about the process itself? Here’s how it typically unfolds.

Procedure of IUI with 2 follicles

Intrauterine insemination (IUI) with two follicles involves:

1. Ovulation Stimulation: Fertility drugs are administered to stimulate the production of multiple follicles.
2. Monitoring: Regular ultrasound checks ensure follicles reach a mature size.
3. Timing Ovulation: A trigger shot is given to induce ovulation, typically 24-36 hours before IUI.
4. Sperm Preparation: Sperm is collected, washed, and prepared to increase concentration.
5. Insemination: Washed sperm is inserted into the uterus using a thin catheter.
6. Follow-up: A pregnancy test is conducted about two weeks after the procedure.

What follows after the IUI procedure? Let’s delve into what to expect post-treatment.

What to expect after IUI with 2 follicles?

Here’s what to expect regarding results, side effects, and post-operative care:

Results

The chances of IUI success with 2 follicles are usually higher compared to IUI with a single follicle. The presence of two mature follicles increases the likelihood of fertilization and conception, as it provides multiple opportunities for the sperm to meet the egg.

While success rates can vary depending on individual circumstances and clinic protocols, the overall chances of achieving pregnancy are generally better with two follicles.

Additionally, having two follicles can raise the chance of a multiple pregnancy, notably twins, which is more common in successful IUIs with multiple follicles than with a single follicle.

Side Effects

• Ovarian Hyperstimulation Syndrome (OHSS): Though rare in IUI compared to IVF, stimulating the ovaries to produce multiple follicles can sometimes lead to OHSS, which is characterized by swollen, painful ovaries.
• Hormonal Changes: The medications used to stimulate the ovaries can cause side effects such as mood swings, headaches, and abdominal discomfort.
• Spotting: Some women experience light spotting after the procedure, which is generally not a cause for concern.

Post-Operative Care

• Rest: It’s usually advised to take it easy for the rest of the day after the procedure, although you can return to normal activities the next day.
• Monitoring Symptoms: Watch for any severe pain or swelling in the abdomen, as these could be signs of complications such as OHSS.
• Follow-Up: A pregnancy test is typically recommended about two weeks after the IUI to check for pregnancy.
• Avoid High-Impact Activities: It’s generally recommended to avoid high-impact activities until after the pregnancy test or as advised by your healthcare provider.
  

Now that you’re aware of what to expect after IUI with 2 follicles, let’s delve into the next crucial aspect: the Cost of IUI with 2 follicles.

Cost of IUI with 2 follicles

The cost of IUI can vary, but it is generally less expensive than in vitro fertilization (IVF). IUI with two mature follicles might increase costs slightly due to additional medications and monitoring but remains a cost-effective option for many couples.

The cost of IUI with 2 mature follicles ranges from ₹10,000 to ₹50,000. This price variation can be influenced by factors such as the clinic’s location, the complexity of the patient’s fertility issues, and the medications used to stimulate follicle growth.


Curious about the expenses? Visit the clinic to learn more about the cost of IUI with 2 follicles and explore financial options tailored to your needs.

Now that you’re prepared for the journey ahead after IUI with 2 follicles, let’s explore real-life success stories that inspire hope.

Success Stories

Neha Parekh, 27

After two years of trying to conceive, we decided to try IUI. With two mature follicles, we were hopeful but nervous. On our second cycle, we finally got the positive test we had been dreaming of. Our beautiful baby girl is now six months old, and we couldn’t be happier.

Anushka Sharma, 29

Our fertility journey was challenging, but IUI with two follicles was a game-changer for us. On our first attempt, we were thrilled to learn we were expecting. The process was straightforward and gave us the miracle we were praying for. Our son was born healthy and strong.

 FAQs

Reference links

https://www.ajog.org/article/S0002-9378(07)00630-8/abstract
https://academic.oup.com/humupd/article/14/6/563/632578#:~:text=Multifollicular%20growth%20is%20associated%20with,for%20more%20than%20two%20follicles.